Injectable microparticle-gel system for prolonged and localized lidocaine release. I.In vitro characterization
نویسندگان
چکیده
منابع مشابه
Injectable microparticle-gel system for prolonged and localized lidocaine release. I. In vitro characterization.
Current treatment protocol for postoperative pain is to infuse anesthetic solution around nerves or into the epidural space. This clinical practice is beset by the short duration of the anesthetic effect unless the infusion is continuous. Continuous infusion, however, requires hospitalization of the patients, thereby increasing medical costs. In addition, it also causes systemic accumulation of...
متن کاملInjectable microparticle-gel system for prolonged and localized lidocaine release. II. In vivo anesthetic effects.
Current treatment protocols for postoperative pain are beset by either the short duration of the anesthetic effect or requirement of hospitalization of the patients. We reported herein a novel treatment by applying to the surgical site a biodegradable microparticle-gel system for prolonged and localized release of encapsulated anesthetic drugs. In a previous publication, lidocaine-loaded poly(D...
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ژورنال
عنوان ژورنال: Journal of Biomedical Materials Research
سال: 2004
ISSN: 0021-9304,1097-4636
DOI: 10.1002/jbm.a.30086